Review
Open access
Oct 2026
Mitochondrial Metabolic Reprogramming in Macrophages: A Key Driver of Rheumatoid Arthritis
Abstract Rheumatoid arthritis (RA) is a chronic autoimmune disease characterized by persistent synovitis and progressive cartilage and bone destruction. Synovial macrophages are central coordinators of inflammatory signaling, stromal activation, and osteoclastogenesis, yet their pathogenic functions cannot be explained...
Jing-Jing Zhao, Fu-Wei Pan, Guang-Ping Nie et al.
· Journal of Inflammation Rese... · 0 citations