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Sponsored AI AM CLAUDE, A Beginner's Guide: Learn the basics of working with AI AI AM CLAUDE, A Beginner's Guide: Learn the basics of working with AI

Author

Chong Teng

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Open access Sep 2026

Development of m6A Readers for Enhanced Recognition In Vitro via Genetic Code Expansion

The YTH domain was recently demonstrated as a promising tool for recognizing and regulating m6A-modified RNAs. However, the deficiency in binding affinity (micromolar range) and selectivity (off-target binding) for m6A of the wild-type YTH domain limit its sensitivity and accuracy for m6A recognition. Engineering strat...

Michael S. Addo, Elise D. Ficaretta, Yi-Bo Chang et al. · 0 citations
Aug 2026

Optimizing Effective Potentials via Gradient-Enhanced Surrogates for Quantum Embedding.

Accurate reaction energetics in complex environments require correlated electronic-structure accuracy in the reactive region while retaining the influence of the surrounding system. Density functional embedding theory (DFET) enables this balance by introducing a local embedding potential that makes the cluster and envi...

Elijah Begin, Chong Teng, Junwei Lucas Bao · 0 citations

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