Open access
Sep 2026
Tumor-derived CTHRC1 mediates ITGB3-dependent osteoclast differentiation to promote prostate cancer bone metastasis
The findings identify CTHRC1 as a novel mediator in the bone microenvironment, providing a potential therapeutic target for inhibiting the occurrence and progression of PCa bone metastasis.
Tao Xie, Tian-Ming Peng, Qu Li et al.
· Oncogene · 0 citations