Chong-Xin Tao

Kinetically Regulated Isothermal Amplification Enables Enhanced microRNA Sensing via Solid-State Nanopores.

Solid-state nanopore sensing has become a common method for biomarker detection, but it still faces challenges with short nucleic acid markers (<50 nt) such as microRNAs (miRNAs). A simple but effective signal amplification strategy, specifically optimized for nanopore detection, is therefore needed. Here, we have deve...