Cyproconazole-Induced Systemic Neuro-Immunotoxicity: An Integrated In Vivo and In Silico Study of Oxidative Stress, NLRP3-Related Inflammatory Signaling, and Cholinergic Disruption.
Cyproconazole (CYPRO), a widely used triazole fungicide, is detected across food and environmental matrices, raising concerns about chronic low-dose human exposure. Its potential to disrupt the neuro-immune interface, particularly the cross-talk between cholinergic signaling and the NOD-like receptor pyrin domain-conta...