A robust liquid chromatography–tandem mass spectrometry method for accurate quantification of omeprazole in human plasma: Integration of International Council for Harmonisation guidelines for pharmacokinetic application
A simple, rapid, and reliable bioanalytical method based on protein precipitation coupled with LC-MS/MS was developed and validated for the quantification of omeprazole in human plasma. The method employs protein precipitation with acetonitrile for sample preparation, offering a fast and efficient extraction proces...