Open access
Sep 2026
Causal Inference and Pathway Embeddings with Real-World Data for Enhanced Trial Design Across Diseases
Randomized controlled trials (RCTs) are often considered the gold standard for causal inference, but their implementation can be costly, time-consuming, and sometimes infeasible due to ethical or practical constraints. The so-called target trial emulation framework introduced the systematic use of observational data fo...
Margot Blanchon, Carrie Heller, Maksim Kriukov et al.
· Mathematical and Computation... · 1 citation