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Sponsored Artificial Intelligence: A Modern Approach, Global Edition Artificial Intelligence: A Modern Approach, Global Edition

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Chris Pickford

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Open access Oct 2026

Preclinical Characterization of ADCT-241, an Exatecan-Based Antibody-Drug Conjugate Against PSMA for the Treatment of Metastatic Castration-Resistant Prostate Cancer.

Prostate-specific membrane antigen (PSMA) is a type II transmembrane glycoprotein with elevated expression in primary and metastatic prostate cancer (PCa) compared with normal prostate tissues; with low levels in renal proximal tubules, small intestine, and the brain. PSMA is a clinically validated target and is associ...

Asma Jabeen, B. Leatherdale, Rebecca Martin et al. · 0 citations

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