Author

Christian Brandt

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Open access Oct 2026

Dose-dependent Effects of Cenobamate on Brivaracetam Pharmacokinetics: A Retrospective Cohort Study.

BACKGROUND Cenobamate is a novel antiseizure medication that inhibits cytochrome P450 2C19 (CYP2C19), which is involved in brivaracetam metabolism. Therefore, a pharmacokinetic interaction is assumed. In this study, the authors investigated the effects of cenobamate comedication on serum brivaracetam concentrations....

Eyad Hayani, A. Hagemann, D. Klimpel et al. · Therapeutic Drug Monitoring · 0 citations

Open access Aug 2026

High-frequency visual stimulation can increase medial temporal lobe ripple oscillation density

Flickering visual stimulation can evoke neural oscillations, which can influence ongoing brain activity. Electrophysiological recordings of neural oscillations in the ripple band (80–180 Hz) show that these high-frequency oscillations occur in the neocortex and the hippocampus, that they phase-synchronize across long d...

Julian Keil, Victor Hernandez-Urbina, Liam Doherty et al. · Communications Medicine · 0 citations

#large language models Open access Aug 2026

Using large language models to investigate patients' and caregivers' perceptions on SUDEP: A case study with an online epilepsy population.

BACKGROUND Sudden Unexpected Death in Epilepsy (SUDEP) is a leading cause of epilepsy-related mortality, yet remains under-communicated in clinical practice. Social Media Listening (SML) is a novel method using natural language processing and machine learning to retrieve real-world data. This study uses SML and explore...

Nicole Brazda, T. Andreu, Philipp Cimiano et al. · Epilepsy & Behavior · 0 citations