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Author

Christophe Chesné

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Open access Aug 2026

Behaviour of iPSC-Derived and Donor-Derived Hepatic Stellate Cells in Organoid Cultures Is Highly Variable and Contributes to Fibrotic Outcome

It is suggested that HSC heterogeneity, whether iPSC-derived or donor-derived, is an important factor in fibrotic output and response variability in human liver organoid models and should be considered in model design, interpretation and comparison between studies.

Yu-Wei Yang, Mina Kazemzadeh Dastjerd, Ayla J. Smout et al. · 0 citations

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