Traumatic brain injury (TBI) often leads to subtle white matter damage that remains undetected on conventional MRI. Diffusion kurtosis imaging (DKI), an extension of diffusion tensor imaging (DTI), provides complementary information on non-Gaussian water diffusion and is sensitive to complex white-matter microstructure...
Ji-Qing Huang, Ali Al-Husseini, Yi Chen et al.· 0 citations
Purpose Brain ageing involves interrelated changes in molecular processes, neuroinflammatory mechanisms, brain macro- and microstructure, sleep physiology, and cognition. The 50 to 70 years age range represents a critical transition period, in which these subtle alterations may precede measurable cognitive decline and...
Antoine Jacquemin, Ji-Qing Huang, N. Beliy et al.· bioRxiv· 0 citations
Tissue-specific smoothing strategies substantially influence both statistical sensitivity and voxel-wise model fitting in qMRI analyses, suggesting that smoothing should be viewed as a region-dependent optimization problem and highlight voxel-wise LL mapping as a region-dependent optimization problem.
Antoine Jacquemin, Christophe Phillips· bioRxiv· 0 citations
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