Christopher D. Wiley

Targeting Mitochondrial Dysfunction with Mdivi-1 Confers Therapeutic Protection in Cell Culture and Mouse Models of Mustard Keratopathy

Mustard keratopathy, caused by exposure of the cornea to sulfur or nitrogen mustard vesicants, chemical warfare agents, can lead to severe and often irreversible vision loss. Despite considerable efforts to develop medical countermeasures, including anti-inflammatory, antioxidant, anti-fibrotic, and anti-angiogenic the...