Open access
Oct 2026
Multi-Site Quantitative Benchmarking of Neu5Gc-Bearing N-Glycans Using Matrix-Matched LC-MS calibration.
It is found that the DMB-LC-FLR assay's specificity and sensitivity were insufficient for Neu5Gc detection in human samples due to noise overwhelming the Neu5Gc signal, and LC-MS confidently resolved Neu5Gc signals from noise, even at low abundance.
Nicholas J. DeBono, Edward S. X. Moh, J. Poole et al.
· Glycobiology · 0 citations