Author

Christopher O. Barnes

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Open access Jul 2026

Structural characterization of broadly neutralizing and potent V1/V2 apex antibodies elicited in rhesus macaques through immunization 2267435

High-resolution cryo-EM structures of bnAbs isolated over a year after the priming immunization revealed that these antibodies recapitulate the binding modes and structural features observed in human-derived V1/V2 apex bnAbs isolated from chronically infected donors, further supporting the utility of nonhuman primate m...

Ipsita Krishnamurthy, Xuduo Li, R. Andrabi et al. · Journal of Immunology · 0 citations

Jul 2026

Structural characterization of antibodies binding the conserved central helix and membrane-proximal lower stalk of coronavirus spike glycoprotein 2248624

Monoclonal antibodies from COVID-19 convalescent donors are identified that target two conserved epitopes in the S2 domain of the coronavirus Spike glycoprotein: the central helix and the lower stalk, advancing knowledge of two conserved and structurally vulnerable sites within the coronavirus S2 subunit.

Adonis A. Rubio, M. Abernathy, Davide F. Robbiani et al. · Journal of Immunology · 0 citations