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Sponsored AI Networking Cookbook: Practical recipes for AI-assisted network automation and development AI Networking Cookbook: Practical recipes for AI-assisted network automation and development

Author

Chuanfeng Liu

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Open access Sep 2026

Discovery of Potent EGFR Inhibitors for Del19 and L858R/T790M Mutants Through Structure‐Based Virtual Screening and Biological Evaluation

With its novel molecular scaffold and mutant‐selective inhibitory profile, XJ2‐2 represents a promising lead compound for overcoming NSCLC drug resistance and advancing the development of next‐generation EGFR inhibitors.

Ting Xu, Yu-Chi Zhao, Meng-Fei Chen et al. · 0 citations
Aug 2026

Design, synthesis, and antitumor evaluation of celastrol derivatives targeting PRDX3.

In vivo efficacy evaluation demonstrated that 10d exhibited significantly superior tumor suppression in a subcutaneous xenograft model of H1975 tumors compared to celastrol, without causing notable systemic toxicity such as significant body weight loss.

Yu-Chi Zhao, Han-Shuang Cai, Li-Juan Zuo et al. · 0 citations

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