Author

Chuan-Jin Luo

2 papers indexed here

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Open access Aug 2026

Exploration of core mitochondrial genes and epigenetic regulatory mechanisms in cardiac arrest via multi-omics integrated analysis

There is a lack of effective molecular biomarkers for the early identification of the risk of cardiac arrest. Mitochondrial dysfunction is widely recognised as being involved in the pathophysiological process of cardiac arrest, but the upstream epigenetic regulatory mechanisms remain unclear. This study takes DNA...

Qing Miao, Gui-Ting Zhou, Jiahua Liang et al. · Clinical Epigenetics · 0 citations

Open access Sep 2026

HMOX2-driven crosstalk between vascular aging and heart failure: A multimodal bioinformatics and explainable machine learning approach with experimental validation

Purpose The molecular mechanisms linking vascular aging (VA) and heart failure (HF) remain elusive, hindering therapeutic strategies for their comorbidity. This study aimed to identify key biomarkers and pathways potentially involved in VA-HF synergy using integrative computational approaches. Methods We analyzed the G...

Jin-Ze Li, Gui-Ting Zhou, Qiao-Chu Wang et al. · PLoS ONE · 0 citations