Chuan-Kai Dai

Conditional Generation and Inpainting of Non-Coding RNA Sequences with Masked Discrete Diffusion

Designing functional non-coding RNA (ncRNA) is fundamental to synthetic biology and RNA therapeutics, yet generative modelling for ncRNA has received far less attention than protein design. We present RNA-MDLM, a framework that extends Masked Discrete Language Models (MDLM) to the conditional generation and inpainting...