Hydrogen-Bond Encoding in a Structurally Minimal Cyclochiral Monomer Enables Assembly of Large Cavities Displaying Supramolecular Isomerism.
Large, well-defined molecular cavities are typically constructed from rigid covalent scaffolds, which can limit structural adaptability and increase synthetic complexity. Here, we introduce a hydrogen-bond encoded supramolecular strategy that enables structurally minimal, flexible monomers to assemble into discrete ful...