Ligand Fishing for Xanthine Oxidase Inhibitors From Brassica rapa L. via Bioaffinity Ultrafiltration‐HPLC‐MS/MS: Mechanistic Insights and In Vitro Anti‐Hyperuricemic Activity
Hyperuricemia is a prevalent metabolic disorder arising from dysregulated purine metabolism, wherein xanthine oxidase (XOD) serves as the key rate‑limiting enzyme catalyzing the final oxidation of hypoxanthine and xanthine to uric acid. Although Brassica rapa L. (chamagu) has been previously reported to exert ant...