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Chuan-Yu Yao

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Open access Aug 2026

Stage-specific signaling modulation generates low-tumorigenicity thyroid progenitors from human pluripotent stem cells

Introduction Human pluripotent stem cell (hPSC)-derived thyroid cells hold great promise for thyroid disease modeling, drug screening, and cell replacement therapies. However, the direct differentiation of hPSCs into functional thyroid follicles remains challenging, suggesting deficient specification of hPSC-derived pr...

Li-Li Dong, Man-Zhen Peng, Chuan-Yu Yao et al. · 0 citations

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