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Sponsored AI AM CLAUDE, A Beginner's Guide: Learn the basics of working with AI AI AM CLAUDE, A Beginner's Guide: Learn the basics of working with AI

Author

Chuan Zhang

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Open access Sep 2026

ISGylation promotes ALDOA stability and PKM2-dependent activation to fuel colorectal cancer metabolism

ISG15 overexpression in cancers has emerged as a diagnostic marker and therapeutic target. This study identifies ISGylation, a post-translational modification mediated by ISG15, as a critical driver of CRC progression through metabolic reprogramming and oncogenic signaling. Clinical and multi-omics analyses reveal el...

Ye Wang, Peng Yang, Chi Jin et al. · 0 citations

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