Open access
Sep 2026
The mechanism of NEDD4 attenuating intracerebral hemorrhage injury through restoring glymphatic function by ubiquitin-mediated degradation of LPAR1.
BACKGROUND Intracerebral hemorrhage (ICH) induces severe neurological injury, and the glymphatic system plays a critical role in post-ICH brain recovery. This study investigated the role of neural precursor cell expressed developmentally down-regulated protein 4 (NEDD4), an E3 ubiquitin ligase, in modulating glymphatic...
Cong Tan, Xiao-Bing Zheng, Li Peng et al.
· Brain Research Bulletin · 0 citations