Author

Chun-Chen Ko

2 papers indexed here

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Sep 2026

Advanced glycation end products promote ferroptotic injury in human renal tubular epithelial cells through the miR-362-3p/SLC7A11/GPX4 Axis.

Diabetic nephropathy (DN) is a major cause of chronic kidney disease, yet the mechanisms underlying tubular epithelial injury remain incompletely understood. Advanced glycation end products (AGEs) contribute to diabetic renal damage, but their role in ferroptosis-associated tubular injury is not fully defined. This stu...

Yi-Cheng Chu, Vijesh Kumar Yadav, Iat-Hang Fong et al. · Life Science · 0 citations

Open access Jul 2026

LARS Inhibition Overcomes Regorafenib Resistance in Hepatocellular Carcinoma via Ferroptosis and Drug Metabolism.

BACKGROUND Regorafenib improves outcomes in advanced hepatocellular carcinoma (HCC), but acquired resistance limits its durable therapeutic benefit. The metabolic and redox mechanisms driving regorafenib resistance remain incompletely defined. METHODS Regorafenib-resistant Huh7 and Hep3B cell (RegR-) models were gene...

Tung-Yao Tsai, Hsuan-Hwai Lin, Yi-Chiao Cheng et al. · European Journal of Pharmace... · 1 citation