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Chun-Feng Tan

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Open access Sep 2026

Stress-induced helicase DHX36 controls neuroinflammation.

Neurons in the aging brain experience sustained inflammatory, proteostatic, and genotoxic stress, accompanied by the accumulation of non-canonical nucleic acid structures such as G-quadruplexes (G4s). Using a G4-binding probe and mass spectrometry, we identified the G4 helicase DHX36 enriched in the aged mouse brain, p...

V. J., Rocio Diaz Escarcega, Chun-Feng Tan et al. · 0 citations

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