Review
Sep 2026
Recent advances in the medicinal chemistry of HSV-1 inhibitors (2020-2025): Emerging targets, modalities, and translational challenges.
Herpes simplex virus type 1 (HSV-1) causes widespread human infection, for which curative therapies remain unavailable. First-line TK-dependent nucleoside analogues such as acyclovir fail to eradicate latent virus and show limited activity against drug-resistant variants, highlighting an urgent unmet medical need. This...
Qiao-Mei Zhou, Bao-Hu Li, Ye-Hong Dai et al.
· European journal of medicina... · 0 citations