Open access
Jul 2026
Shared CRISPR arrays underpin type I-A/I-B coexistence.
A shared-array logic in which Cas6a/Cas6b-compatible processing routes a single pre-crRNA to multiple type I effectors providing a potential mechanism for subtype co-existence, a plausible explanation for array-less (or "orphan") interference modules, and an evolutionary bet-hedging strategy that prevents Acrs from shutting down immunity wholesale are uncovered.
Kunming Liu, Chunjiang Ren, Xinyue Liu et al.
· Protein & Cell · 0 citations