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Chun-Jie Wu

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Open access Oct 2026

A dual-function XCL1-CD40L mRNA adjuvant potentiates cancer vaccines by coordinating DC recruitment and maturation

Despite the significant promise of mRNA tumor vaccines in treating solid tumors, their clinical response rate is constrained by the low effectiveness of antigen presentation resulting from the immune-suppressive tumor microenvironment (TME). Conventional type 1 dendritic cells (cDC1) are pivotal in antigen cross-pr...

Chun-Jie Wu, Wan-Xuan Shao, Ya-Di Liu et al. · 0 citations

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