Author

Chun-Kit Kwok

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Open access Oct 2026

Landscape and mutational dynamics of G-quadruplexes across the complete human genome

G-quadruplexes (G4s) are alternative DNA structures with diverse biological roles, but their examination in highly repetitive parts of the human genome has been hindered by the lack of reliable sequencing technologies. Recent long-read based genome assemblies have enabled their characterization in previously inac...

Nikol Chantzi, Shi Wei. Liew, Aurell Wijaya et al. · Genome Biology · 0 citations

Open access Jul 2026

RNA G-quadruplex structure recognition by chimeric peptides

The rational design of chimeric peptides that combine a de novo selected peptide with a native peptide derived from the endogenous DHX36 protein suggests that chimeric peptide design provides a useful strategy for developing selective rG4-targeting ligands and modulating functional nucleic acid structures.

Xi Mou, Jiuming Wang, Yanruisheng Shao et al. · Nucleic Acids Research · 0 citations