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Chun-Lei Ji

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Review Open access Sep 2026

S100B in brain–gut–liver crosstalk: from glial activation to multiorgan inflammation

S100 calcium-binding protein B (S100B) is conventionally viewed as a marker of astrocytic injury, blood–brain barrier (BBB) disruption, and neurological disorders. Emerging evidence places S100B within the broader brain–gut–liver axis of inflammatory signaling. This review proposes that S100B is a glial-derived integra...

Qi Liu, Ming Yan, Chun-Lei Ji et al. · 0 citations

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