Chunrong Wang

Whole‐Exome Sequencing Reveals the Genetic Landscape and Genotype–Phenotype Spectrum of Dystonia in a Chinese Cohort

ABSTRACT Aims To systematically characterize the genetic landscape of dystonia in a Mainland Chinese cohort, where over 60% of patients currently lack a molecular diagnosis due to limited large‐scale genomic studies. Methods Whole‐exome sequencing (WES) was performed in a cohort of 147 clinically diagnosed dystonia pat...

Longitudinal changes in DTI-ALPS index are associated with clinical progression and brainstem atrophy in spinocerebellar ataxia type 3.

Serum Metabolomic Profiles Unveil Biomarkers and Core Metabolic Pathways in Multiple System Atrophy Patients.

This study defined the serum metabolomic signature of MSA and highlighted novel biomarkers, pathological mechanisms, and therapeutic targets deserving further validation.

An Atlas of Modifiers of Age at Onset in Huntington's Disease.

This study conducted the first comprehensive Mendelian randomization (MR) analysis of AAO causal determinants in HD, highlighting modifiable biological and lifestyle factors that may underpin future preventive or therapeutic interventions.