Review
Open access
Oct 2026
Gut microbiome-shaped chemotherapy responses across cancer types: mechanisms of resistance, biomarkers, and targeted interventions
Cytotoxic chemotherapy remains an important component of multimodal treatment for many solid tumors, but resistance and dose-limiting toxicities continue to constrain clinical benefit. The gut microbiome can influence chemotherapy response through microbial drug biotransformation, metabolite signaling, intestinal-barri...
Ting Shao, Ming-Hui Li, Shao-Lin Li et al.
· Frontiers in Immunology · 0 citations