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Chun-Yi Yang

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Jul 2026

Skeleton-aware SAM2 adaptation for topology-preserving angiographic vessel segmentation

The proposed Skeleton-Aware SAM2 improves both overlap-based and topology-aware performance over strong baselines and topology-aware loss variants and suggests that explicit morphology-guided conditioning provides useful structural bias for topology-sensitive angiographic vessel segmentation under domain shifts.

Shuang Liang, Chun-Yi Yang, Zhicheng Liu et al. · 0 citations
#diffusion models Open access Sep 2026

Mechanism-Guided Antimicrobial Peptide Design through Membrane-Surface Fingerprinting and Graph Diffusion

Membrane-MaSIF, an MD-derived membrane surface matching model designed to capture peptide–membrane compatibility beyond sequence-level AMP labels, is developed and provides a mechanism-aware strategy for Gram-negative AMP discovery and optimization.

Zhen-Yu Ma, Si-Xin Tian, Meng-Meng Sheng et al. · 0 citations

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