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Chun-Yu Liu

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Open access Aug 2026

Targeted phagocytosis of TNF-α by CAR macrophages restores immune homeostasis in arthritis

Under stimulation with synovial fluid from arthritis patients, anti-TNFα CAR-M decreased TNF-α and IL-6 levels and drove macrophages toward an M2-like anti-inflammatory state, significantly alleviating inflammatory activation, clinical symptoms, and joint pathologies.

Mei-Qi Wang, Jie Zhu, Chun-Yu Liu et al. · 0 citations

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