Open access
Sep 2026
Preclinical evaluation of AL-001, a gene therapy for wet age-related macular degeneration
Suprachoroidal administration of AL-001 is well tolerated and provides durable, targeted aflibercept expression with pronounced antiangiogenic efficacy, and these results support AL-001 as a promising, long-acting therapeutic candidate for wAMD.
Xuan Liu, Hai-Yan Liu, Lei Wang et al.
· Frontiers in Genetics · 0 citations