Jul 2026
The Multifaceted Roles of the Hippo-Yes-Associated Protein (YAP)/Transcriptional Coactivator with a PDZ-Binding Motif Pathway in Regulating the Tumor Microenvironment.
This work discusses recent advances in understanding how this pathway modulates the immune landscape, cancer-associated fibroblasts, and tumor vasculature and outlines how YAP/TAZ drives fibroblast activation, matrix stiffening, and promotes cancer-associated fibrosis.
Zihao Sui, Ting Wang, Chunling Yi
· Cold Spring Harbor Perspecti... · 0 citations