Yeast polysaccharide YE-2-1 promoted ingenol-3-angelate production in Euphorbia peplus cambium meristematic cell cultures.
Ingenol-3-angelate (PEP005), the main bioactive compound among the diterpenoid esters from Euphorbia peplus, has a good therapeutic effect on skin tumors. However, the supply of PEP005 still has problems with low yield. Yeast extract (YE) was selected as the elicitor to improve the contents and explore the biosynthetic...