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Open access Oct 2026

METTL3 Increases Temozolomide Resistance in MGMT‐Negative Glioblastoma by Enhancing CBX5 mRNA Stability in an m6A‐IGF2BP2‐Dependent Manner

ABSTRACT Aims We examined whether chromobox protein 5 (CBX5) contributes to temozolomide (TMZ) resistance in O6‐methylguanine‐DNA methyltransferase (MGMT)‐negative glioblastoma (GBM) and whether it is regulated by methyltransferase‐like 3 (METTL3)‐dependent N6‐methyladenosine (m6A) and insulin‐like growth factor 2 mRNA...

Hui Deng, Ruo-Yu Chen, Dao-Hong Qu et al. · 0 citations
Open access Sep 2026

SDF4 is a potential biomarker for diagnosis and severity assessment in patients with systemic lupus erythematosus

The implementation of refined management of systemic lupus erythematosus (SLE) poses a considerable challenge in clinical practice. In this study, we evaluated serum stromal cell-derived factor 4 (SDF4) as potential biomarkers for SLE diagnosis, disease severity, and prognosis. We determined the SDF4 level...

Xi Chen, Xuan-Zhe Yang, Jing Chen et al. · 0 citations

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