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Ci Ren

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Open access Aug 2026

Rapid normal fibroblast‐tumor crosstalk promotes cancer‐associated fibroblast‐like activation and attenuates mitomycin C cytotoxicity in bladder cancer

Results show that NF‐tumor crosstalk is rapid, bidirectional and functionally relevant to MMC response in vitro, and NFs can rapidly acquire CAF‐like activation features following tumor‐derived stimulation and contribute to a stromal context associated with EMT‐like plasticity and reduced MMC‐induced cytotoxicity in vitro.

Jinhui Gao, Cindy Xinyu Ji, Ci Ren et al. · Journal of cell communicatio... · 0 citations