Author

Ci Song

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Open access Aug 2026

Association between low skeletal muscle mass assessed by deep learning-based CT and MASLD: a prospective cohort study

To explore the role of abdominal skeletal muscle mass in metabolic dysfunction-associated steatotic liver disease (MASLD) incidence and resolution, we established two independent cohorts in a Chinese population. This study included 3139 participants without MASLD (incidence cohort) and 1130 MASLD patients (resolution c...

Ya-Ping Wang, Jing Lu, Jiu-Lou Zhang et al. · Diabetology & Metabolic Synd... · 0 citations

Open access Aug 2026

Large-scale whole-genome sequencing reveals the landscape and health implications of de novo mutations.

Paternal and maternal aging exhibited distinct mutational patterns, with maternal DNM accumulation accelerating at advanced ages, and in vitro embryo manipulation was associated with increased early post-zygotic mosaic mutations, particularly C > A substitutions linked to delayed neurocognitive development at 1 year.

N. Qin, Jun-Cheng Dai, Yue Jiang et al. · Nature Medicine · 1 citation