Clare Latta

Orphan GPR84 facilitates uropod de-adhesion at multiple steps during leukocyte extravasation.

Leukocyte migration through venular walls is an essential component of effective immunity. While the key molecular players driving the initial steps of this response are known, the terminating signals remain unclear. Here, we identify a conserved role for GPR84 family GPCRs in the successful completion of the final sta...