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Review Open access Oct 2026

Targeting lysine acetyltransferase 6A/B in cancer: a conceptual and translational review of epigenetic regulation, immune microenvironment remodeling, and the dual-compartment hypothesis

While lysine acetyltransferase 6A (KAT6A; MOZ/MYST3) and 6B (KAT6B; MORF/MYST4) function as context-dependent oncogenic drivers—with KAT6B also displaying tissue-specific tumor-suppressive roles—their pharmacological targeting holds promise as a therapeutic avenue. This conceptual and translational review synthesizes e...

Cong Ma, Jing-Ru Wang, Guan-Hua Qiao et al. · 0 citations
Open access Aug 2026

Explainable Multimodal Machine Learning Predicts 90-Day Treatment Failure in Older Patients with Fragility Fractures of the Pelvis

Pretreatment integration of pelvic ring mechanics, frailty and routinely available systemic biomarkers enables clinically relevant enrichment of older patients at risk of TF90 and is best positioned to support intensified surveillance and structured reassessment rather than determine operative treatment.

Kangwei Wang, Yulin Cao, Nan Gao et al. · 0 citations

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