Open access
Sep 2026
Hierarchical Nanoplatform Integrating Oxidative–Acidic Microenvironment Remodeling and Bone Homeostasis Modulation for Diabetic Bone Defect Therapy
ABSTRACT Diabetic craniofacial bone defects exhibit unsatisfactory repair attributed to synergistic oxidative stress, local acidification and disordered bone immunity, whereas conventional mono‐functional biomaterials are incapable of synchronously resolving these interlocked pathological cascades. Herein, a hierarchic...
Xu Chen, Xing-Yu Zhu, Zhixin Qiu et al.
· Advancement of science · 0 citations