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Conor J. Kearney

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Review Open access Oct 2026

A guide to studying tumour-T-cell interactions using in vitro coculture assays.

T cells are central mediators of antitumour immunity and are the cellular basis of many successful cancer immunotherapies, including immune checkpoint blockade, T-cell receptor (TCR)-engineered therapies and chimeric antigen receptor (CAR) T cells. However, clinical responses remain variable, and many tumours evade or...

Nooshin Khoshdoozmasouleh, Conor J. Kearney · 0 citations

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