Author

Craig A. Goodman

2 papers indexed here

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Open access Sep 2026

β-hydroxy-β-methylbutyrate improves fast-twitch muscle function, histopathology and mitochondrial respiration in the D2.mdx dystrophic mouse.

Duchenne muscular dystrophy (DMD) is a severe inherited muscle disorder caused by mutations that eliminate the protein, dystrophin, resulting in disrupted protein homeostasis, mitochondrial dysfunction, chronic inflammation and progressive muscle degeneration. The leucine metabolite, β-hydroxy-β-methylbutyrate (HMB), h...

Nicholas Giourmas, Hannah Lalunio, Memphis Calzoni et al. · Journal of Physiology · 0 citations

Open access Jul 2026

Sex-divergent skeletal muscle remodeling emerges early in cancer cachexia.

Results show that cachexia progression in this model is sexually dimorphic and skeletal muscle undergoes extensive remodeling before overt wasting and sex-divergent pre-cachectic windows that may guide early biomarker discovery and therapeutic strategies aimed at preventing progression and improving quality of life in...

Chris Karagiannis, Alastair A. E. Saunders, Rachel E. Thomson et al. · American Journal of Physiolo... · 0 citations