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Author

Craig B. Wilen

2 papers indexed here

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Open access Aug 2026

Mucosal vaccine-elicited IgA is protective against zoonotic Betacoronavirus challenge

Current vaccines for respiratory viruses are primarily administered intramuscularly. Messenger RNA-lipid nanoparticle (LNP)-based intramuscular vaccination for respiratory coronaviruses induces strong systemic IgG antibody responses; they do not consistently elicit IgA in the upper and lower respiratory tracts. Using a...

Junghwa Seo, Emma Buck, Bryan Machani et al. · 0 citations
Open access Sep 2026

Aminopeptidase N is a receptor for hedgehog merbecoviruses.

Merbecoviruses, closely related to the Middle East respiratory syndrome coronavirus, circulate in hedgehogs throughout Europe and Asia, raising concerns about zoonotic transmission to humans and domestic animals. However, it is not clear how these viruses enter host cells. Here we tested three coronavirus receptors fro...

M. Jin, Victoria A. Jefferson, Zhe Zhao et al. · 0 citations

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