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Sponsored Design Multi-Agent AI Systems Using MCP and A2A: Engineer your own Pyt Design Multi-Agent AI Systems Using MCP and A2A: Engineer your own Pyt

Author

Crescenzo Frascogna

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Open access Sep 2026

β4-integrins safeguard nuclear mechanics to suppress prostate cancer progression

Prostate cancer (PCa) progression is accompanied by profound alterations in cell-extracellular matrix (ECM) adhesion, nuclear architecture and mechanical adaptability, yet the molecular mechanisms linking these processes remain poorly understood. Hemidesmosomes (HDs), formed by α6β4-integrins, anchor epithelial cells t...

Anette Schmidt, Rong Wei, Paulina Nastały et al. · 0 citations
Open access Aug 2026

Substrate curvature and stiffness equivalence in governing cell mechanosensing

Mechanosensing enables cells to perceive and interpret their mechanical microenvironment, including forces, stiffness and topography. Although focal adhesions (FAs) are central to this process, their structural adaptation to mechanical stimuli remains poorly understood. Here, we uncover FA tilting - the inclination of...

Crescenzo Frascogna, Valeria Panzetta, Valentina Mollo et al. · 0 citations

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