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Author

Crystal L. Mackall

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Review Oct 2026

Toward the next generation of CAR T cell therapies for cancer.

The clinical lessons learned from the now substantial experience with commercial CAR T cells and clinical trials are summarized and three waves shaping next-generation development are discussed: multi-engineered and logic-gated CAR T cells, rational combination strategies, and in vivo CAR T cell generation.

D. Usta, Crystal L. Mackall · 0 citations

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