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Sponsored Artificial Intelligence: A Modern Approach, Global Edition Artificial Intelligence: A Modern Approach, Global Edition

Author

Cui Zhang

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Sep 2026

Ustekinumab combined with upadacitinib promotes endoscopic healing in moderate-to-severe Crohn's disease with anti-TNF-α failure.

BACKGROUND Anti-tumor necrosis factor-α (TNF-α) therapy failure in moderate-to-severe Crohn's disease (CD) represents a major clinical challenge. However, the exploration of advanced combination therapy offers a promising direction. This study compared the efficacy of ustekinumab (UST) plus upadacitinib (UPA) with eith...

Chang-Qin Liu, Qing-Gang Geng, Lu Lu et al. · 0 citations

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