Integrated multi-omics analyses reveal the role of PAXX in colorectal cancer progression and the tumor immune microenvironment
PAXX is a DNA double-strand break repair factor involved in classical non-homologous end joining. Although elevated PAXX expression has been reported in colon cancer, its functional role and downstream mechanisms in colorectal cancer (CRC) remain incompletely defined. This study investigated the role of PAXX in CRC p...