Author

D. Aguillón

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Open access Sep 2026

Genomic Landscape of Early-Onset and Familial Latin American Parkinson's Patients

Background Parkinson's disease (PD), the most common neurodegenerative movement disorder, is commonly thought of as an aging and sporadic disease; however, 5-14% of individuals experience disease onset before the age of 50 years (early-onset PD; EOPD) and about 20% have a positive family history. In the case of both EO...

E. Waldo, H. M. Chaparro-Solano, M. Isayan et al. · medRxiv · 0 citations

Open access Jul 2026

Remote digital cognitive assessment in a trial‐ready Alzheimer's disease cohort: A scalable approach for early intervention studies

ABSTRACT INTRODUCTION Early detection of cognitive decline in Alzheimer's disease (AD), particularly in preclinical stages, is critical for evaluating therapeutic interventions. Traditional cognitive assessments often require lengthy in‐person visits, and may therefore limit scalability for younger, trial‐ready populat...

A. Aschenbrenner, H. Wilks, Matthew S. Welhaf et al. · Alzheimer's & Dementia · 1 citation

Open access Jul 2026

Associations among mild behavioral impairment, cognition, and brain pathology in preclinical autosomal dominant Alzheimer's disease

Abstract INTRODUCTION The Mild Behavioral Impairment Checklist (MBI‐C) captures neuropsychiatric symptoms in individuals at risk of dementia. In this study, we examined MBI‐C scores in autosomal dominant Alzheimer's disease (ADAD). METHODS We included 83 cognitively unimpaired presenilin‐1 E280A mutation carriers and 1...

Catarina Tristão-Pereira, D. Vásquez, Jorge Alcina et al. · Alzheimer's & Dementia · 0 citations